Popularity ranking · United States

The 85 most popular Medicines in United States

This curated ranking covers the 85 largest medicines in United States, ordered by estimated audience size from Rascasse's anonymized search-behavior signals. GoodRx, Tylenol and Pfizer lead the list with a combined estimated audience of 22M people. Across all 85 entries the average audience size is 1.4M, and the largest, GoodRx, reaches around 11M people in United States. Audience size is the estimated number of unique people in United States who actively engage with each medicine, derived from search demand signals. Rankings reflect search-behavior signals collected across United States and are updated quarterly.

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How to read this list

Rank

Position in the Top 85, sorted by audience size from largest to smallest. Updated quarterly.

Audience size

Estimated number of unique people in United States who actively engage with this audience, derived from anonymized search-behavior signals.

Country share

Share of the global audience that is active in United States. A higher value means the audience is more locally concentrated here.

Avg age

Average age in years across the people who engage with this audience in United States, derived from anonymized search-behavior signals. A dash means demographic data is not yet available.

Female share

Share of women among the people who engage with this audience in United States. 50% is gender-balanced; values above mean female-skewed, below mean male-skewed.

Ranking

Rank Audience Audience size Avg age Female share Subtype
1 GoodRx 11M 43.2 64.8% Medicine
2 Tylenol 6M 41.2 56.4% Medicine
3 Pfizer 5.4M 48.2 59.9% Medicine
4 Ro 5.3M 41.2 54.5% Medicine
5 Benadryl 4.7M 42.4 55.2% Medicine
6 Mucinex 4.3M 43.9 60.3% Medicine
7 Zyrtec 4M 43.1 53.8% Medicine
8 MiraLAX 3.5M 42.4 65.8% Medicine
9 Sudafed 3.3M 41.6 50.0% Medicine
10 Pepto-Bismol 3.2M 42.8 59.1% Medicine
11 Metamucil 2.9M 43.4 59.1% Medicine
12 OptumRx 2.8M 39.9 54.5% Medicine
13 Imodium (medication) 2.7M 42.4 58.6% Medicine
14 Pepcid 2.5M 43.8 60.7% Medicine
15 Flonase 2.5M 44.5 51.9% Medicine
16 Dramamine 2M 43.0 60.9% Medicine
17 Amway 1.9M 36.5 78.1% Medicine
18 Advil 1.9M 41.7 56.5% Medicine
19 Herbalife 1.9M 36.7 63.6% Medicine
20 TheraFlu 1.9M 40.4 58.9% Medicine
21 Claritin 1.9M 42.0 56.6% Medicine
22 Aleve 1.9M 45.3 61.0% Medicine
23 Nyquil 1.9M 42.3 56.3% Medicine
24 Novartis 1.8M 48.6 57.3% Medicine
25 Neosporin 1.7M 40.5 46.0% Medicine
26 Excedrin 1.7M 42.5 62.4% Medicine
27 Robitussin 1.7M 43.6 56.9% Medicine
28 Dr. Scholl's 1.6M 49.1 71.3% Medicine
29 Xyzal 1.5M 42.8 55.2% Medicine
30 Alka-Seltzer 1.5M 42.4 60.1% Medicine
31 GlaxoSmithKline 1.5M 42.1 50.5% Medicine
32 Tums 1.5M 42.7 59.2% Medicine
33 Bristol-Myers Squibb 1.5M 52.4 54.1% Medicine
34 Motrin 1.5M 39.8 63.4% Medicine
35 Bayer 1.3M 45.9 48.3% Medicine
36 Novo Nordisk 1.3M 49.8 54.2% Medicine
37 Allegra 1.2M 37.1 52.5% Medicine
38 Gas-X 1.2M 43.4 63.5% Medicine
39 Preparation H 1.1M 46.4 51.6% Medicine
40 Monistat 1.1M 41.8 84.1% Medicine
41 Emergen-C 1.1M 46.2 60.1% Medicine
42 Band-Aid 999k 43.4 46.1% Medicine
43 Abbott Laboratories 991k 44.0 55.6% Medicine
44 Zicam 986k 41.7 53.4% Medicine
45 Theragun 971k 39.7 50.0% Medicine
46 Afrin 953k 41.1 54.7% Medicine
47 Merck & Co. 823k 46.3 56.9% Medicine
48 Delsym 773k 43.6 57.2% Medicine
49 Vagisil 598k 39.3 83.9% Medicine
50 Boehringer Ingelheim 533k 46.4 53.3% Medicine
51 BC Powder 529k 40.4 61.1% Medicine
52 Sanofi 496k 46.3 61.9% Medicine
53 Bengay 479k 40.0 53.7% Medicine
54 BASF 477k 45.1 23.6% Medicine
55 Vicks 450k 42.2 54.6% Medicine
56 Hims & Hers 446k 42.7 61.8% Medicine
57 Naloxone 443k 42.8 57.1% Medicine
58 Prilosec OTC 434k 43.2 57.3% Medicine
59 Shaklee 378k 44.6 74.6% Medicine
60 Nasacort 370k 45.1 58.3% Medicine
61 Title Boxing Club 366k 36.5 39.7% Medicine
62 Hyperice 342k 39.7 50.0% Medicine
63 Isopure 258k 37.6 42.8% Medicine
64 Piping Rock 248k 37.5 56.3% Medicine
65 L'il Critters 248k 45.3 61.0% Medicine
66 Chloraseptic 242k 39.9 53.4% Medicine
67 Compound W 205k 41.6 51.9% Medicine
68 Rolaids 190k 42.9 59.1% Medicine
69 Lurasidone 143k 42.1 63.2% Medicine
70 Nature's Way (supplements) 133k 43.8 59.8% Medicine
71 9Round 121k 40.6 49.7% Medicine
72 Goody's Powder 110k 40.2 61.1% Medicine
73 LetsGetChecked 85k 43.6 70.5% Medicine
74 ThermaCare 84k 43.0 43.4% Medicine
75 Vitafusion 71k 46.1 57.9% Medicine
76 Efferdent 67k 42.4 61.8% Medicine
77 Varilux 58k 48.0 56.2% Medicine
78 Polydimethylsiloxane 53k 30.8 57.3% Medicine
79 AZO (supplements) 16k 39.5 53.9% Medicine
80 Doppelherz 10k 34.1 85.9% Medicine
81 Beano 9.6k 42.3 61.7% Medicine
82 Puritan's Pride 4.2k 44.1 60.4% Medicine
83 Meridol 3.7k 38.6 60.4% Medicine
84 Cetilar 1.3k 40.8 56.8% Medicine
85 Bausch & Lomb 879 42.5 64.4% Medicine

Want the full picture for any of these audiences?

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Frequently asked questions

How is this list of the most popular medicines compiled?

Rascasse aggregates anonymized search-behavior signals across United States and ranks each medicine by its estimated audience size. Only entries with at least 5 measured entities are listed.

How often is the list updated?

The ranking is updated quarterly from the latest search-behavior data and re-published as a static page.

What is the largest medicine in United States?

GoodRx currently leads with an estimated audience of 11M people in United States.

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