Popularity ranking · United States

The 85 most popular Medicines in United States

This curated ranking covers the 85 largest medicines in United States, ordered by estimated audience size from Rascasse's anonymized search-behavior signals. GoodRx, Ro and Pfizer lead the list with a combined estimated audience of 21M people. Across all 85 entries the average audience size is 1.4M, and the largest, GoodRx, reaches around 10M people in United States. Audience size is the estimated number of unique people in United States who actively engage with each medicine, derived from search demand signals. Rankings reflect search-behavior signals collected across United States and are updated quarterly.

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How to read this list

Rank

Position in the Top 85, sorted by audience size from largest to smallest. Updated quarterly.

Audience size

Estimated number of unique people in United States who actively engage with this audience, derived from anonymized search-behavior signals.

Country share

Share of the global audience that is active in United States. A higher value means the audience is more locally concentrated here.

Avg age

Average age in years across the people who engage with this audience in United States, derived from anonymized search-behavior signals. A dash means demographic data is not yet available.

Female share

Share of women among the people who engage with this audience in United States. 50% is gender-balanced; values above mean female-skewed, below mean male-skewed.

Ranking

Rank Audience Audience size Avg age Female share Subtype
1 GoodRx 10M 43.2 64.8% Medicine
2 Ro 5.6M 41.2 54.5% Medicine
3 Pfizer 5.4M 48.2 59.9% Medicine
4 Benadryl 5M 42.4 55.2% Medicine
5 Tylenol 4.6M 41.2 56.4% Medicine
6 Zyrtec 4.2M 43.1 53.8% Medicine
7 Sudafed 3.6M 41.6 50.0% Medicine
8 Mucinex 3.5M 43.9 60.3% Medicine
9 MiraLAX 3M 42.4 65.8% Medicine
10 OptumRx 2.9M 39.9 54.5% Medicine
11 Imodium (medication) 2.9M 42.4 58.6% Medicine
12 Herbalife 2.3M 36.7 63.6% Medicine
13 Metamucil 2.2M 43.4 59.1% Medicine
14 Pepto-Bismol 2.2M 42.8 59.1% Medicine
15 Dramamine 2.1M 43.0 60.9% Medicine
16 TheraFlu 2M 40.4 58.9% Medicine
17 Advil 2M 41.7 56.5% Medicine
18 Nyquil 2M 42.3 56.3% Medicine
19 Amway 2M 36.5 78.1% Medicine
20 Flonase 1.9M 44.5 51.9% Medicine
21 Pepcid 1.9M 43.8 60.7% Medicine
22 Robitussin 1.8M 43.6 56.9% Medicine
23 Neosporin 1.8M 40.5 46.0% Medicine
24 Novartis 1.7M 48.6 57.3% Medicine
25 Claritin 1.7M 42.0 56.6% Medicine
26 Aleve 1.6M 45.3 61.0% Medicine
27 Alka-Seltzer 1.6M 42.4 60.1% Medicine
28 Tums 1.6M 42.7 59.2% Medicine
29 Bristol-Myers Squibb 1.5M 52.4 54.1% Medicine
30 GlaxoSmithKline 1.5M 42.1 50.5% Medicine
31 Dr. Scholl's 1.4M 49.1 71.3% Medicine
32 Excedrin 1.3M 42.5 62.4% Medicine
33 Allegra 1.3M 37.1 52.5% Medicine
34 Gas-X 1.2M 43.4 63.5% Medicine
35 Abbott Laboratories 1.2M 44.0 55.6% Medicine
36 Xyzal 1.2M 42.8 55.2% Medicine
37 Preparation H 1.2M 46.4 51.6% Medicine
38 Motrin 1.2M 39.8 63.4% Medicine
39 Novo Nordisk 1.2M 49.8 54.2% Medicine
40 Bayer 1.2M 45.9 48.3% Medicine
41 Monistat 1.2M 41.8 84.1% Medicine
42 Emergen-C 1.1M 46.2 60.1% Medicine
43 Band-Aid 1M 43.4 46.1% Medicine
44 Theragun 1M 39.7 50.0% Medicine
45 Zicam 949k 41.7 53.4% Medicine
46 Merck & Co. 821k 46.3 56.9% Medicine
47 Delsym 821k 43.6 57.2% Medicine
48 Afrin 782k 41.1 54.7% Medicine
49 Puritan's Pride 632k 44.1 60.4% Medicine
50 BC Powder 567k 40.4 61.1% Medicine
51 Boehringer Ingelheim 531k 46.4 53.3% Medicine
52 Vagisil 525k 39.3 83.9% Medicine
53 Bengay 510k 40.0 53.7% Medicine
54 Hims & Hers 469k 42.7 61.8% Medicine
55 Hyperice 468k 39.7 50.0% Medicine
56 Sanofi 468k 46.3 61.9% Medicine
57 Prilosec OTC 464k 43.2 57.3% Medicine
58 Naloxone 443k 42.8 57.1% Medicine
59 Vicks 425k 42.2 54.6% Medicine
60 Shaklee 425k 44.6 74.6% Medicine
61 BASF 390k 45.1 23.6% Medicine
62 Nasacort 389k 45.1 58.3% Medicine
63 Title Boxing Club 372k 36.5 39.7% Medicine
64 Isopure 287k 37.6 42.8% Medicine
65 Chloraseptic 258k 39.9 53.4% Medicine
66 Piping Rock 256k 37.5 56.3% Medicine
67 Compound W 216k 41.6 51.9% Medicine
68 Rolaids 200k 42.9 59.1% Medicine
69 Lurasidone 143k 42.1 63.2% Medicine
70 9Round 125k 40.6 49.7% Medicine
71 Goody's Powder 114k 40.2 61.1% Medicine
72 ThermaCare 87k 43.0 43.4% Medicine
73 LetsGetChecked 80k 43.6 70.5% Medicine
74 Vitafusion 75k 46.1 57.9% Medicine
75 Efferdent 73k 42.4 61.8% Medicine
76 Nature's Way (supplements) 66k 43.8 59.8% Medicine
77 Varilux 57k 48.0 56.2% Medicine
78 Polydimethylsiloxane 53k 30.8 57.3% Medicine
79 AZO (supplements) 17k 39.5 53.9% Medicine
80 Beano 10k 42.3 61.7% Medicine
81 L'il Critters 8.7k 45.3 61.0% Medicine
82 Doppelherz 7.7k 34.1 85.9% Medicine
83 Meridol 2.4k 38.6 60.4% Medicine
84 Bausch & Lomb 1.3k 42.5 64.4% Medicine
85 Cetilar 1.3k 40.8 56.7% Medicine

Want the full picture for any of these audiences?

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Frequently asked questions

How is this list of the most popular medicines compiled?

Rascasse aggregates anonymized search-behavior signals across United States and ranks each medicine by its estimated audience size. Only entries with at least 5 measured entities are listed.

How often is the list updated?

The ranking is updated quarterly from the latest search-behavior data and re-published as a static page.

What is the largest medicine in United States?

GoodRx currently leads with an estimated audience of 10M people in United States.

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